Both self-efficacy and quality of life of the caregivers improved or maintained by the interventions, compared with the controls (p0.05). Results: It was found that, although the quality of life improved by the trainings in the patient intervention groups, compared with the control group (p0.05). The 12-Item Short-Form Health Survey (SF-12), the General Self-Efficacy Scale (GSES) were applied to patients and caregivers and the Reintegration to Normal Living Index (RNLI) were applied to patients only, before discharge and 3 months after discharge. Methods: In this randomized, controlled trial, 59 patients and their caregivers were randomly allocated to receive discharge with education (via a webpage or booklet) or a standard of care discharge without intervention (i.e. We argue that we can proceed faster to evaluating interventions within international pragmatic trials.īackground & Objectives: This study was carried out to evaluate the effects of discharge training on quality of life and self-efficacy in stroke patients and their informal caregivers and reintegration to normal living in patients only. The observed differences could result in a different potential for recovery and variation in treatment effects across trials. The present study highlighted important clinical differences across countries whilst using an identical study protocol. #JUNG DA YEON DOWNLOAD EXERCISE VIDEOS TRIAL#No effect modification was observed and trial outcomes did not change after controlling for cross-country differences. The level of contamination was higher (P = 0.040) among Dutch controls. Australian patients were recruited earlier poststroke (P<0.001), spent less time in exercise therapy (P<0.001) and had a shorter length of stay (P<0.001). Dutch patients were younger (P = 0.005) and had a lower functional status (P = 0.001). Most patients suffered an ischemic stroke, were in the subacute phase and participated with their partner. In addition, we explored if factors that were significantly different across countries caused variation in these trial outcomes. We examined if study setting significantly moderated the trial outcomes: Hospital Anxiety and Depression Scale, Fatigue Severity Scale and General Self-Efficacy Scale, measured at 8- and 12 weeks follow-up. Patient characteristics, compliance, usual care and process measures were compared across countries. Patients with stroke and their caregivers were randomly allocated to an 8-week caregiver-mediated exercises intervention (N = 63 31 Australian and 32 Dutch) or to a control group (N = 66 32 Australian and 34 Dutch). To compare two identically protocolized trials conducted in different western countries in order to identify factors that may have caused variation in secondary trial outcomes.Ĭomparative study based on individual patient data (N = 129) from two randomized controlled trials, conducted in hospitals and rehabilitation facilities in the Netherlands (N = 66) and Australia (N = 63). However, variation in treatment effects across countries have been given little attention. The evidence for rehabilitation interventions poststroke lack sufficient robustness.
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